Not entirely sure if "amputees" react to having lost a limb the right way now. They stick into the hospital, not willing to do anything at all waiting for the prostetics to be researched/built.
This isnt so much of an issue with my kingdom (I only have to research prostetics, then tinkering becomes useless again), but if you start a new kingdom and someone looses a limb, they will sit around in bed being useless for a long, long time.
Or it forces the player to de-assign the hospital and re-assign it if someone needs medical attention. Sort of the wrong micromanagement, if you ask me.